Program Management
340B Program Management – We offer complete 340B program management, from registration and TPA transitions to implementation, optimization, and ongoing support. Our team also assists with EMR changes, pharmacy model reviews, and education to keep your program running smoothly.
Questions? You’re covered.
Our 340B Program Management includes end-to-end support for covered entities, including HRSA Registration & Recertification, TPA Selection & Transitions, and Implementation. We take care of the details, so your program runs smoothly and compliantly.
We provide Pharmacy Profitability and Model Reviews, explore new partnership opportunities, and support TPA changes. Our goal is to maximize financial efficiency while keeping your program compliant and aligned with operational objectives.
We manage Program Changes of all kinds, including EMR Changes with TPA Support. Plus, we provide Continuing Education & Pharmacy Education, so your team stays current on 340B requirements and best practices.
Client Success Story: Rebuilding a 340B Program for Long-Term Performance
A regional health system partnered with ACI after years without dedicated strategic oversight of its 340B program. Over time, key program components had become outdated, resulting in declining savings and limited visibility into performance.
The Challenge
The organization was facing multiple structural issues, including:
- An outdated contract pharmacy network
- Underperforming split-billing operations
- Lack of centralized program strategy or performance tracking
- Significant decline in 340B program savings
Without intervention, the program was not positioned for long-term sustainability or optimization.
Our Approach
ACI conducted a comprehensive program assessment and implemented targeted improvements across core operational areas:
- Restructured contract pharmacy network and third-party administrator (TPA) arrangements
- Implemented ESP with updated pharmacy designations and data submission processes
- Optimized system configurations to improve covered entity and eligible location performance
- Established quarterly performance benchmarking to support ongoing accountability and optimization
The Outcome
Within 12 months of implementation:
- Program savings increased by more than 100%
- The health system gained a clear, sustainable 340B strategy supported by ongoing performance oversight
The program transitioned from fragmented oversight to a structured, measurable, and scalable model.
A New Program Built for Compliance and Long-Term Success
Following the success of a 340B program optimization engagement, a peer organization engaged ACI to support the launch of its first-ever 340B program.
The Challenge
As a new covered entity, the organization needed end-to-end support to ensure:
- Proper program structure from inception
- Full HRSA compliance
- A scalable foundation for long-term operational success
- Avoidance of costly retroactive corrections or redesign
Our Approach
ACI provided full lifecycle implementation support, including:
- Comprehensive program readiness assessment
- HRSA registration of the covered entity, eligible child sites, and contract pharmacy network
- Design and implementation of a compliant, scalable 340B program structure
- Strategic setup to support long-term operational efficiency and compliance monitoring
The Outcome
The organization successfully launched a fully compliant and optimized 340B program, built with sustainability and scalability from day one.
This foundation enabled immediate operational readiness while minimizing future compliance risk and administrative rework.
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